98% Azelaic Acid Powder CAS 123-99-9 | Cosmetic API Manufacturer
98% Azelaic Acid Powder CAS 123-99-9 | Cosmetic API Manufacturer
Azelaic Acid API,CAS 123-99-9,98% azelaic acid powder,azelaic acid for acne,azelaic acid cosmetic raw material,Custom Peptide Synthesis,Bulk Peptide Supplier,cGMP Manufacturing
Source high-purity 98% Azelaic Acid powder (CAS 123-99-9) directly from cGMP manufacturer. HPLC verified cosmetic API for anti-acne & brightening formulation R&D.
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Description
cGMP STANDARD COSMETIC INGREDIENT SUPPLIER
Azelaic Acid 98%
CAS No.: 123-99-9
Purity (HPLC)≥ 98.0%
Molecular FormulaC9H16O4
Molecular Weight188.22 Da
AppearanceWhite Crystalline Powder
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Scientific Overview & Manufacturing Excellence
We specialize in the contract manufacturing and stable market supply of high-purity 98% Azelaic Acid, a naturally occurring, saturated straight-chain dicarboxylic acid. Utilizing an advanced secondary recrystallization purification technology, our finished active material is presented as a uniform white crystalline powder characterized by exceptional dispersibility in topical cream, lotion, and serum systems.
The entire production workflow operates within GMP-standardized clean workshops with comprehensive batch traceability. We strictly control heavy metal and microbial parameters to comply with rigorous international cosmetic-grade and medical skincare standards. Every batch is calibrated via High-Performance Liquid Chromatography (HPLC) to guarantee a stable 98.0% purity, providing formulators worldwide with a safe, non-irritating active ingredient designed for acne management and dermal brightening lines.
Pharmacological Mechanisms & Skin Regulation Profile
Bacteriostatic & Anti-Comedogenic Activity
Azelaic Acid exerts a marked bacteriostatic effect, specifically inhibiting the synthesis of cellular proteins in harmful skin flora such as Cutibacterium acnes. Concurrently, it regulates epidermal cell turnover by softly metabolizing excess keratin and reducing abnormal follicular hyperkeratinization. This dual mechanism drastically mitigates the formation of closed comedones and inflammatory acne lesions.
Tyrosinase Inhibition & Tone Brightening
As a competitive inhibitor of tyrosinase, it acts precisely on hyperactive melanocytes without affecting normal skin pigmentation. It powerfully disrupts the biochemical pathways of melanin synthesis, effectively fading post-inflammatory hyperpigmentation (dark acne marks) and refining rough, dull complexions to restore an even, radiant skin tone.
Anti-Inflammatory & Barrier Preservation
Compared to traditional exfoliating acids (e.g., salicylic acid or AHA), Azelaic Acid is significantly milder. It scavenges reactive oxygen species (ROS), providing excellent soothing relief for facial redness, stinging, and barrier irritation, making it highly compatible for sensitive, acne-prone, and rosacea-associated skincare formulas.
API Formulation Objectives & Target Application Scenarios
Meeting international cosmetic-grade safety compliance, this low-irritation API is engineered to seamlessly integrate into versatile skincare manufacturing formulas (Recommended addition ratio: 5%–15%):
✔ Acne Management Systems: Core active raw material for acne treatment essences, overnight acne creams, and closed comedone care lotions.
✔ Sensitive Skin & Rosacea Care: Integral for developing redness-soothing repair serums and compromised skin barrier restoration complexes.
✔ Pigmentation & Tone Correction: Perfect for brightening toners, post-acne mark fading creams, and even-tone facial care applications.
✔ Professional Medical Beauty: Deployed in salon special compound formulas, gentle exfoliating masks, and oil-control balancing skincare series.
Technical Specifications & Quality Standards
| Product Identity | Azelaic Acid (Dicarboxylic Acid Cosmetic API) |
|---|---|
| Physical Characteristics | White Crystalline Powder (Uniform & Dispersible) |
| Testing Method & Purity | HPLC Analysis; ≥ 98.0% |
| Physicochemical Integrity | • Moisture: ≤ 0.5% • Ash Content: ≤ 0.3% • Mesh Size: 80–100 Mesh |
| Heavy Metals & Safety Limits | Heavy Metal (Pb) ≤10ppm; Arsenic (As) ≤2ppm. Zero irritating residual impurities. Safe for long-term topical skincare addition. |
| Flexible Packaging Configurations | • Sample Scale: 1kg vacuum aluminum foil bag • Bulk Wholesale: 25kg sealed industrial fiber drum *Private label outer packaging and trial specifications are fully supported. |
| Storage & Shelf Life | Store tightly sealed in a cool, dry, and dark environment. Avoid high temperature and humidity to prevent crystal agglomeration. Validity is 24 months. |
Frequently Asked Questions (Formulation & Procurement)
What is the recommended adding dosage of Azelaic Acid in skincare formulas?
The conventional addition range in commercial cosmetic formulas is 5%–15%. Formulators should adjust the specific proportion based on product positioning. We recommend utilizing lower concentrations for sensitive barrier repair formulations, while up to 15% is utilized for intensive acne and brightening treatments. A patch test is strongly suggested before mass production.
What skin types is 98% Azelaic Acid best suited for?
It is exceptionally suited for oily acne-prone skin, sensitive skin prone to redness (such as rosacea-associated erythema), and skin with prominent post-inflammatory hyperpigmentation (dark acne marks). Its chemical property is significantly milder, delivering less dermal irritation than traditional fruit acids (AHA) and salicylic acid (BHA).
Can you provide complete documents for overseas cosmetic brand filing and customs clearance?
Yes. Manufactured under stringent ISO9001 and GMP guidelines, we supply a complete technical package for our global clients. This includes full HPLC chromatogram test reports, Certificate of Analysis (COA), Material Safety Data Sheets (MSDS), and strict microbial and heavy metal safety certificates to fully support your brand registration and border clearance.
Do you offer formulation technical guidance alongside raw material supply?
Absolutely. As a direct factory supplier, we offer more than just bulk material. We provide comprehensive one-stop services including free pre-purchase test samples, customized packaging solutions, and professional technical guidance regarding dosage references, emulsion compatibility, and finished product stability optimization.
Shaanxi Sunrise Pharmaceutical Co., Ltd.
Senior Independent Site Operations Specialist: Betty
📧 Email: betty@pharma-sunrise.com|💬 WhatsApp: +86 18092760627