Silybin 98% HPLC (CAS 22888-70-6) | Milk Thistle Extract API

Silybin 98%,CAS 22888-70-6,Milk Thistle Extract,Hepatoprotective API,Silybum marianum,Silymarin active compound,Shaanxi Sunrise

Source premium Silybin 98% HPLC (CAS 22888-70-6) from Shaanxi Sunrise. High-purity hepatoprotective API derived from Milk Thistle. Full COA & GMP support.



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Description



✓ ISO 9001:2015 Certified            ✓ High-Purity Silybin API (≥98%)            ✓ cGMP-Aligned Production
Shaanxi Sunrise Pharmaceutical Direct API
Silybin 98% HPLC 3

Highly Purified Hepatoprotective Botanical API

Standard Commercial Supply                25 KG / Drum (R&D Pilot Samples Supported)

Silybin 98% (CAS 22888-70-6) | API

CAS: 22888-70-6                Milk Thistle Extract
Specification≥ 98.0% (HPLC)
Botanical SourceSilybum marianum (Seed)
Molecular Formula/WeightC₂₅H₂₂O₁₀ | 482.44
AppearanceOff-White Fine Powder
Shelf Life & Storage24 Months | Cool, dry, light-protected
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Technical Support:                    betty@pharma-sunrise.com

Stringent Quality Control Limits

Test ItemStandard Limit
Loss on Drying≤ 1.0%
Residue on Ignition≤ 0.5%
Heavy Metals (Total)≤ 10.0 ppm
Solvent ResidueComplies with USP <467>
Total Plate Count≤ 1,000 cfu/g (Salmonella: Negative)

Pharmacology & Formulation Notes

Silybin (also known as Silibinin) is the major active constituent of silymarin. It possesses profound hepatoprotective properties by acting as a free radical scavenger and modulating lipid peroxidation in liver cell membranes.                    

                   Formulation Pro-Tip: Due to its lipophilic nature and poor water solubility, Silybin is frequently complexed with phosphatidylcholine (phytosomes) or incorporated into lipid-based delivery systems to significantly enhance its oral bioavailability in finished dietary supplements.

Technical & Formulation FAQ

What is the difference between Silymarin and Silybin?

Silymarin is a complex mixture of flavonolignans extracted from milk thistle seeds, typically standardized to 80%. Silybin is the single most potent active molecule purified from this complex. Using 98% pure Silybin allows formulators to achieve exact, concentrated dosing for targeted liver therapies without the bulk of the entire extract.

What extraction solvents are used in your process?

Our extraction process strictly utilizes food-grade ethanol and ethyl acetate. Residual solvents are thoroughly removed during the final crystallization and vacuum drying stages, ensuring complete compliance with USP <467> limits.

Legal Disclaimer

This product is a raw material intended solely for industrial manufacturing, formulation into dietary supplements, or R&D. Buyers are responsible for ensuring final product efficacy and regulatory compliance in their respective regions.

Shaanxi Sunrise Pharmaceutical Co., Ltd. | Industrial API & Botanical Extract Supply