Abaloparatide Acetate Salt API CAS 247062-33-5 | Peptide Manufacturer
Abaloparatide Acetate Salt API CAS 247062-33-5 | Peptide Manufacturer
Abaloparatide Acetate API,CAS 247062-33-5,Abaloparatide Acetate,Custom Peptide Synthesis,Bulk Peptide Supplier,PTH1R agonist,osteoanabolic peptide,cGMP Peptide Manufacturing
Source high-purity Abaloparatide Acetate peptide API (CAS 247062-33-5) directly from cGMP manufacturer. Purity ≥98.0% by HPLC. Flexible packaging from mg to bulk kg for osteoporosis formulation R&D.
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Description
cGMP STANDARD PHARMACEUTICAL PEPTIDE SUPPLIER
Abaloparatide Acetate Salt
CAS No.: 247062-33-5
Purity (HPLC)≥ 98.0%
Molecular FormulaC176H304N56O51
Molecular Weight≈ 4020.62 Da
Peptide Content / AcetateCustom / Controlled
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Scientific Overview & High-Quality Custom Peptide Synthesis
We specialize in the contract manufacturing and stable market supply of high-purity Abaloparatide Acetate API. Utilizing advanced solid-phase peptide synthesis (SPPS) platforms and evaluated under rigorous in-house quality control frameworks, this material maintains exceptional reproducibility and an analytical purity of ≥98% via HPLC methodology to line up perfectly with international regulatory expectations.
Our cGMP-compliant synthesis workflows successfully minimize batch-to-batch structural variations. We stably support global generic developers and academic institutions throughout the product development lifecycle—delivering versatile packaging matrices ranging from milligram-scale R&D reference standard solutions to bulk kilogram industrial manufacturing lots.
Pharmacological Profile & API Formulation Targets
Mechanism of Action (MoA)
As a synthetic 34-amino-acid analog of human PTHrP(1-34), Abaloparatide functions as a highly potent, selective agonist targeting the PTH1R (parathyroid hormone 1 receptor) expressed on osteoblasts. Upon receptor binding, it preferentially triggers sustained Gs-cAMP-PKA canonical signaling pathway activation. Its unique conformation induces strong osteoblast proliferation and differentiation, with minimal stimulation of osteoclast-driven bone resorption.
Clinical Formulation Benchmarks
Downstream finished preparations using this peptide target structural bone modulation pathways. Finished dosage forms are designed to elevate skeletal mass and optimize bone microarchitecture, yielding clinical references of marked elevations in Bone Mineral Density (BMD) and substantial fracture risk reduction among high-risk postmenopausal osteoporosis demographics.
Pharmaceutical R&D Expansion
Formulation & Generic Exploration: Essential reference material for generic drug ANDA profiling and stability validation.
Novel Delivery Research: Widely adopted as a core raw component in evaluating advanced transdermal peptide patches, oral delivery systems, and foundational academic mappings of skeletal metabolic disorders.
Technical Specifications & Cold Chain Logistics Standard
| Product Identity | Abaloparatide Acetate (Synthetic Peptide API) |
|---|---|
| Physical Characteristics | White or off-white lyophilized powder |
| Testing Method & Purity | HPLC Analysis; Assay ≥ 98.0% |
| Flexible Packaging Options | • Laboratory Tiers: 1–100 mg per protective glass vial • Scaling Tiers: 1 kg per specialized aluminum foil vacuum bag • Commercial Tiers: 25 kg inside heavy-duty industrial fiber drums *Fully customizable packaging configurations are available upon request. |
| Storage & Cold Chain Mandates | Store tightly sealed at sub-zero conditions -20°C ± 5°C. Protect diligently from light and moisture exposure. Avoid repeated freeze-thaw cycles. |
| Shelf Life Reference | 36 months under the proper recommended sealed and low-temperature storage conditions. |
Frequently Asked Questions (Peptide Procurement)
Can you guarantee the peptide sequence accuracy and purity for commercial scaling?
Absolutely. Our Abaloparatide Acetate API undergoes stringent solid-phase peptide synthesis (SPPS). We provide a complete Certificate of Analysis (COA) with every batch, backed by comprehensive HPLC chromatograms (ensuring ≥98% purity) and Mass Spectrometry (MS) data to definitively confirm the exact sequence and molecular weight.
Do you accommodate custom peptide packaging for novel R&D formulations?
Yes. While our standard industrial packaging covers 1kg vacuum bags and 25kg drums, we fully support R&D institutions by providing highly precise mg-scale sterile vials (1-100mg) specifically designed to facilitate early-stage trials, transdermal patch research, or oral delivery system formulation.
How is the -20°C storage requirement managed during international shipping?
To ensure the complete integrity of the lyophilized peptide powder, we deploy specialized cold-chain logistics for all international shipments. The API is securely vacuum-sealed in moisture-proof aluminum foil and shipped utilizing validated temperature-controlled containers equipped with integrated temperature data loggers.
Is this API available for direct clinical or dietary consumption?
No. As an active pharmaceutical ingredient and research chemical, this product is strictly intended for laboratory scientific research and B2B finished drug manufacturing only. It cannot be sold or distributed for direct human clinical medication or as a food additive.
Shaanxi Sunrise Pharmaceutical Co., Ltd.
Senior Independent Site Operations Specialist: Betty
📧 Email: betty@pharma-sunrise.com|💬 WhatsApp: +86 18092760627